IGOB-131® is a patented extract made from African mango seed. It has been studied for weight management, appetite control, blood sugar support, and overall metabolic health. This document explains the main benefits and how it may be used in products.
Main Health Benefits of IGOB-131®
Weight Management
- How it may work: IGOB-131® may help the body store less fat by affecting enzymes and signals involved in fat creation and appetite, including PPARγ and leptin.
- Study results: In a 10-week study, people who took 150 mg of IGOB-131 twice a day had greater reductions in body weight, waist size, and body fat than people who took a placebo (Ngondi et al., 2009).
Appetite Control
- How it may work: IGOB-131® may help the body respond better to fullness signals and may lower hunger signals.
- Possible effect: In studies, participants reported feeling less hungry and eating fewer calories.
Blood Glucose Support
- How it may work: IGOB-13®1 may help the body use insulin more effectively and support healthy blood sugar metabolism.
- Study result: The same 2009 study found improved fasting blood sugar levels in people taking IGOB-131®.
Cholesterol and Triglyceride Support
- How it may work: IGOB-131® may help reduce the creation and storage of fat cells.
- Possible effect: Participants showed lower total cholesterol, LDL cholesterol, and triglycerides, along with higher HDL cholesterol.
Simple Summary of How IGOB-131 May Work
| Action | Effect | Benefit |
| May reduce fat-building signals | May help the body make fewer fat cells | Supports weight management |
| May support adiponectin, a hormone linked to insulin response | May help the body use insulin better | Supports healthy blood sugar levels |
| May reduce an enzyme involved in fat storage | May help reduce fat storage | Supports body fat reduction |
| May reduce ghrelin, a hunger hormone | May reduce hunger | Supports appetite control |
Key References
- Ngondi JL, Oben JE, Minka SR. The effect of Irvingia gabonensis seed extract on body weight and blood lipids of overweight subjects in Cameroon. Lipids Health Dis. 2005;4:12. doi:10.1186/1476-511X-4-12
- Oben J, Ngondi J, Blum K. Inhibition of adipogenesis and glucose uptake by African mango seed extract (IGOB131) is associated with down-regulation of PPARγ, adiponectin, and leptin genes. Lipids Health Dis. 2008;7:44. doi:10.1186/1476-511X-7-44